Tags: pharmacokinetics

Resources (1-20 of 22)

  1. 1-032-S-DigoxinElimination

    17 Aug 2018 | Modeling Scenarios | Contributor(s): Therese Shelton

    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics --...

    https://simiode.org/resources/4993

  2. 1-131-S-CaffeineElimination

    15 Aug 2018 | Modeling Scenarios | Contributor(s): Therese Shelton

    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a reaction in the language of pharmacokinetics -- the study of how drugs...

    https://simiode.org/resources/4976

  3. 1-130-S-AspirinAbsorption

    15 Aug 2018 | Modeling Scenarios | Contributor(s): Therese Shelton

    We model the amount of aspirin absorbed by the human body at a constant rate. This is a ``zero-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the...

    https://simiode.org/resources/4963

  4. 1971-BoyesEtal-Lidocaine In Man

    09 Oct 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Boyes, R. N., D. B. Scott, P. J. Jebson, M. J. Godman, and D. G. Julian, M.D. 1971. Lidocaine in Man.  Clinical Pharmacology and Therapeutics. 12(1): 105-116. Abstract: Plasma levels of...

    https://simiode.org/resources/4262

  5. WangEtAl-Estimating Mixed-Effects Differential Equation Models

    21 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Wang, L., J. Cao 1 , J. O. Ramsay, D. M. Burger , C. J. L. Laporte, and J. K. Rockstroh. Estimating Mixed-Effects Differential Equation Models. Paper. 30 pp. Abstract: Ordinary differential...

    https://simiode.org/resources/4235

  6. Pharmacokinetics – Source Material

    12 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Phamacokinetics –PHAR 7834. https://www.boomer.org/c/p4/?Loc=OUHSC33 . Accessed 11 September 2017. This is a rich source of pharmacokinetics modeling activities and data. These are...

    https://simiode.org/resources/4142

  7. 2004-Rescigno-Use of Pharmacokinetics Models

    11 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Rescigno, Aldo. 2004. On the use of pharmacokinetic models. Phys. Med. Biol. 49: 4657-4676. Abstract:  Extensive use of models in pharmacology, in physiology and in radiotherapy raises...

    https://simiode.org/resources/4129

  8. 2012-Koch-Modeling of Pharmacokinetic and Pharmacodynamics of Cancer and Arthritis

    10 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Koch, Gilbert. 2012. Modeling of Pharmacokinetic and Pharmacodynamics of Cancer and Arthritis. PhD Dissertation. 118 pp. Abstract: Mathematical modeling of pharmacokinetics / pharmacodynamics...

    https://simiode.org/resources/4046

  9. ASHP - Intro to Pharmacokinetics and Pharmacodynamics

    10 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    ASHP.  Intro to Pharmacokinetics and Pharmacodynamics . 18 pp. https://www.ashp.org/-/media/store%20files/p2418-sample-chapter-1.pdf . Accessed 10 September 2017. American Society of...

    https://simiode.org/resources/4023

  10. AccessPharmacy-Pharmacokinetics Of Drug Absorption

    09 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    AccessPharmacy (McGraw Ill). Applied Biopharmaceutics & Pharmacokinetics. Chapter 7.  Pharmacokinetics of Oral. Part of Book series at...

    https://simiode.org/resources/3991

  11. 2014-Shafer-Pharmacokinetis Basis Targeted Controlled Infusion

    09 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Shafer, Steven. The Pharmacokinetic and  Pharmacodynamic Basis of Target Controlled Infusion. 60 pp. https://web.stanford.edu/~sshafer/LECTURES.DIR/Notes/CCIP.DOC . Accessed on 7 September...

    https://simiode.org/resources/3977

  12. 2017-Peletier-Differential Equations First Order Applications

    09 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Peletier, L. A.    Ordinary Differential Equations in Pharmacodynamics. Notes. 23 pp. http://www.math.leidenuniv.nl/~peletier/azcourse04.pdf . Accessed 8 September 2017. Good mix...

    https://simiode.org/resources/3962

  13. 2011-Koch-Pharmacokinetic Intro Biomathematical Modeling

    09 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Koch, Gretchen A. 2011. Mathematical Modelling of Natural Phenomena Drugs in the Classroom: Using Pharmacokinetics to Introduce Biomathematical Modeling . Preprint of artile to appear in...

    https://simiode.org/resources/3944

  14. 1999-KhorashehEtAl-Direct Search Parameter Estimation

    08 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Khorasheh, Farhad , Amir Mahbod Ahmadi, and Abbas Gerayeli, 1999.  Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation . J Pharm Pharmaceut Sci .2...

    https://simiode.org/resources/3866

  15. 1969-Metzler-MathModelOfLSD

    07 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Metzler, Carl M. 1969. A mathematical model for the pharmacokinetics of LSD effect.  Clinical Pharmacology and Therapeutics.  10(5): 737-740 Contains data on performance scores vs....

    https://simiode.org/resources/3842

  16. 1971-Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics

    07 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Metzler, Carl M. , 1971. Usefulness of the Two-Compartment Open Model in Pharmacokinetics. Journal of the American Statistical Association, 66( 333): 49-53 Abstract: Compartment models are...

    https://simiode.org/resources/3840

  17. 1975-RoddaEtAl-OneCompartmentOpenModel

    03 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Rodda, B. E. , C. B. Sampson, and D. W. Smith. 1975.  The One-Compartment Open Model: Some Statistical Aspects of Parameter Estimation. Journal of the Royal Statistical Society. Series C...

    https://simiode.org/resources/3737

  18. 2009-SuSunLiHartford-Comparment Models Pharmacokinetics

    03 Sep 2017 | Potential Scenario Ideas | Contributor(s): Brian Winkel

    Su, Jing,Peng Sun, Xiaodong Li and Alan H. Hartford (all at Merck & Co., Inc, North Wales, PA). 2009. Fitting Compartmental Models to Multiple Dose Pharmacokinetic  Data using SAS PROC...

    https://simiode.org/resources/3735

  19. 2008FoglerGurmen Elements of Chemical Reaction Engineering

    20 Jun 2015 | Potential Scenario Ideas | Contributor(s): H. Scott Fogler, M. Nihat Gurmen

    Fogler, H. Scott and M. Nihat Gurmen. 2008. Elements of Chemical Reaction Engineering:  Strategies for Creative Problem Solving. http://www.umich.edu/~elements/07chap/html/07prof5.htm....

    https://simiode.org/resources/912

  20. 1967-Wagner-Computers in pharmacokinetics

    20 Jun 2015 | Potential Scenario Ideas | Contributor(s): J. G. Wagner

    Wagner,  J. G.  1967. Computers in pharmacokinetics. Clinical Pharmacology and Therapeutics.  8(1)-Part 2:   201-218. This is a seminal paper in pharmacokinetics in which...

    https://simiode.org/resources/885