SIMIODE EXPO 2021 - (M-R3) - Case Study: A Model of Immunotherapy in Prostate Cancer

By Becky Sanft1, Anne Walter2

1. University of North Carolina, Ashville NC USA 2. St. Olaf College, Northfield MN USA

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Abstract

SIMIODE EXPO 2021 - (M-R3) - Case Study: A Model of Immunotherapy in Prostate Cancer

 Adventures in Co-Teaching a Data-Driven Modeling Course

Becky Sanft, University of North Carolina, Ashville NC USA and Anne Walter, St. Olaf College, Northfield MN USA    

This was a presentation made at the SIMIODE EXPO 2021  - see program.

Abstract:  In this session we will guide you through a case study on immunotherapy in prostate cancer that is adaptable to a variety of teaching contexts. We will formulate a system of differential equations that describe the interactions among tumor vaccine cells, immune response, and prostate cancer cells. Data from a prostate-specific antigen (PSA) test will be used to estimate model parameters, and the model will be applied to explore vaccination schedules with the goal of stabilizing the number of tumor cells. Student participants will have the opportunity to engage in the modeling process and see the utility of models for understanding complex systems, making predictions, and identifying further questions. Faculty participants will see a condensed version of how this case study is used in the classroom.

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Researchers should cite this work as follows:

  • Becky Sanft; Anne Walter (2021), "SIMIODE EXPO 2021 - (M-R3) - Case Study: A Model of Immunotherapy in Prostate Cancer," https://simiode.org/resources/8261.

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